{"id":83737,"date":"2020-04-20T20:16:55","date_gmt":"2020-04-20T23:16:55","guid":{"rendered":"https:\/\/megalabs.global\/eng\/?p=83737"},"modified":"2020-04-21T09:48:52","modified_gmt":"2020-04-21T12:48:52","slug":"copcov-el-estudio-clinico-que-prueba-el-uso-profilactico-de-hidroxicloroquina-en-covid-19-en-40-mil-participantes-de-mas-de-50-sitios","status":"publish","type":"post","link":"https:\/\/megalabs.global\/eng\/copcov-el-estudio-clinico-que-prueba-el-uso-profilactico-de-hidroxicloroquina-en-covid-19-en-40-mil-participantes-de-mas-de-50-sitios\/","title":{"rendered":"COPCOV: el estudio cl\u00ednico que prueba el uso profil\u00e1ctico de Hidroxicloroquina en COVID-19"},"content":{"rendered":"

[vc_row row_height_percent=”0″ override_padding=”yes” h_padding=”2″ top_padding=”3″ bottom_padding=”3″ overlay_alpha=”100″ gutter_size=”3″ shift_y=”0″ row_height_use_pixel=””][vc_column column_width_use_pixel=”yes” gutter_size=”3″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ medium_width=”0″ zoom_width=”0″ zoom_height=”0″ column_width_pixel=”800″][vc_column_text]Cloroquina e Hidroxicloroquina son medicamentos antipal\u00fadicos utilizados para el tratamiento y profilaxis de la malaria y tratamiento de artritis reumatoidea y lupus eritematoso sist\u00e9mico. Ambos poseen m\u00e1s de 70 a\u00f1os en el mercado y cuentan con un amplio conocimiento en sus perfiles de seguridad, eficacia y toxicidad.<\/p>\n

COPCOV es un estudio fase 3 intervencional, multic\u00e9ntrico, randomizado (1:1), paralelo, doble ciego, controlado por placebo con 40.000 voluntarios sanos de mayores de 16 a\u00f1os, que trabajan en la salud con contacto con pacientes y que no han sido previamente diagnosticados con COVID-19 y est\u00e1n sanos (NCT04303507). Los brazos de estudio ser\u00e1n dos: (1) placebo y (2) tratamiento con cloroquina (Asia) o hidroxicloroquina (Europa) con una dosis inicial de 10 mg\/kg seguido de 155 mg diarios (250 mg de fosfato de cloroquina o 200 mg de sulfato de cloroquina) por 3 meses. Se evaluar\u00e1 el n\u00famero de casos sintom\u00e1ticos de COVID-19. Se espera que se inicie en el corriente mes de Abril y finalice en Abril de 2021.<\/p>\n

Se espera que este estudio arroje evidencia emp\u00edrica robusta sobre el uso profil\u00e1ctico de Cloroquina e Hidroxicloroquina para infecciones de SARS-CoV-2.<\/p>\n

Bibliograf\u00eda:
\n– Clinical Trials. 2020. Extra\u00eddo de:
\nhttps:\/\/clinicaltrials.gov\/ct2\/show\/NCT04320615?term=NCT04320615&draw=2&rank=1<\/a>[\/vc_column_text][vc_single_image media=”83739″ media_width_use_pixel=”yes” alignment=”center” media_width_pixel=”700″][\/vc_column][\/vc_row][vc_row unlock_row=”” row_height_percent=”0″ override_padding=”yes” h_padding=”2″ top_padding=”3″ bottom_padding=”3″ overlay_alpha=”100″ gutter_size=”3″ column_width_use_pixel=”yes” shift_y=”0″ z_index=”0″ row_height_use_pixel=”” column_width_pixel=”800″][vc_column width=”1\/1″][vc_row_inner row_inner_height_percent=”0″ overlay_alpha=”50″ gutter_size=”3″ border_color=”color-877404″ border_style=”solid” shift_y=”0″ z_index=”0″ css=”.vc_custom_1572995729128{border-top-width: 1px !important;border-bottom-width: 1px !important;padding-top: 18px !important;padding-bottom: 18px !important;}” el_class=”descarga-pdf” limit_content=””][vc_column_inner width=”1\/1″][vc_icon position=”left” icon_image=”82110″ icon_color=”color-877404″ media_size=”42″ text_font=”font-195522″ text_weight=”700″ linked_title=”yes” title=”Descargar Documento” link=”url:%2Fwp-content%2Fuploads%2F2020%2F04%2FCopcov.pdf|title:Copcov|target:%20_blank|”]Copcov<\/p>\n

[\/vc_icon][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/1″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Con 40 mil participantes de m\u00e1s de 50 sitios<\/p>\n","protected":false},"author":1,"featured_media":83738,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96,97],"tags":[],"class_list":["post-83737","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-estudios","category-por-molecula"],"_links":{"self":[{"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/posts\/83737","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/comments?post=83737"}],"version-history":[{"count":0,"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/posts\/83737\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/media\/83738"}],"wp:attachment":[{"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/media?parent=83737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/categories?post=83737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/megalabs.global\/eng\/wp-json\/wp\/v2\/tags?post=83737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}